GAIN (LGD-4033) is an oral SARM & one of the greatest discoveries in the supplement world and represents the pinnacle of years of research. It is a non-steroidal oral product that binds with Androgen Receptors (AR) which produces steroid-like results minus the steroids. It is the closest SARM that can be equated to an anabolic substance in terms of strength. GAIN (LGD-4033) is also the strongest of all the SARMS in terms of the size and strength you can gain.
GAIN (LGD-4033) is anticipated to yield the healing benefits of testosterone with better safety, admissibility and patient acceptance due to tissue-selective mechanism of action and its oral form of administering. It is non-toxic and the side effects are very minimal. Thus, using GAIN (LGD-4033) is recommended if you want to bulk up and drop fat. It won’t affect your liver but a full PCT is advised after running GAIN (LGD-4033). The suppression is higher than other SARMS (but lower than anabolics), thus the need for PCT. Please view our PCT section for a full suite of PCT products.
Dosage:
Concentration: 10mg/mL
Volume: 30mL
GAIN (LGD-4033) should be dosed at 5-10 mg (0.5-1ml), taken orally, once a day in the morning. GAIN (LGD-4033) should be ran 8-12 weeks, with 12 weeks being ideal. Each bottle has 30ml with an average dose been around 1ml (1 full dropper squirt). Each bottle will last around 30 days.Recommended Combinations:

1. Bulking: GAIN (LGD-4033) is the best SARM in its class when it comes to bulking, and 10mg per day for 8 weeks will be plenty as a solo run. However, some experienced athletes will go as high as 15 or 20mg per day. During a bulking cycle with GAIN (LGD-4033) it is essential to make sure to up your calories and heavy weight train at least 3-4 times per week.
2. Fat Loss: A good cutting stack would be combining GAIN (LGD-4033) at 5mg per day with the average doses of MASS (S4) and SHRED (GW-501516). Using GAIN (LGD-4033) by itself is not recommended for cutting, since it has to work in synergy with other SARMs for this purpose.
3. Anabolic Steroid Stack: GAIN (LGD-4033) can be stacked as part of your anabolic steroid cycle to add lean muscle gains and strength without additional side effects. For this, you can add anywhere between 3 and 15mg per day of GAIN (LGD-4033) into your steroid cycle.
4. Re-comping: Re-comping is done by those looking to add lean muscle mass and burn body fat at the same time. GAIN (LGD-4033) is very good at this when ran in conjunction with SHRED (GW-0742), a strict diet, cardio and weight training.
5. AUS LABS BRIDGE STACK: GAIN (LGD-4033) is popularly used in a bridge with MASS (S4) & TEST (RAD-140) to help maintain gains and strength in between traditional steroid cycles. Run 3-5mg per day of GAIN (LGD-4033), and a moderate dose of MASS (S4) & TEST (RAD-140). GAIN (LGD-4033) should not be used during Post Cycle Therapy (PCT).
Ingredients/ HPLC Purity Report
GAIN (LGD-4033): 4-[(2R)-2-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]pyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile, food-grade USP glycol, food-grade ethyl alcohol and essential oils.
Please email [email protected] for the latest HPLC purity report.
Storage:
Cool and dark space like a cupboard or pantry.
Medical References:
- Ligand. (2009, June 17). ligand-initiates-clinical-trial-with-the-selective-androgen. https://www.ligand.com/news-events/press-releases/...
- Fragkaki, AG( 1 ), Sakellariou, P( 1,2 ), Kiousi, P( 1 ), Kioukia-Fougia, N( 1 ), Tsivou, M( 1 ), Angelis, Y( 1 ) & Petrou, M( 3 ) n.d., ‘Human in vivo metabolism study of LGD-4033’, Drug Testing and Analysis, vol. 10, no. 11–12, pp. 1635–1645,
- Ligand. (2011, June 06). ligand-presents-multi-dose-phase-i-data-on-lead-sarm. https://investor.ligand.com/press-releases/detail/...
- Section of Endocrinology, D. a. (2012, March 28). The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young men.https://www.ncbi.nlm.nih.gov/pubmed/22459616
No statements made on this page have been evaluated by the Bundesministerium für Gesundheit (BMG) or the Therapeutic Goods Administration (TGA). These products are not intended to treat, cure or prevent any disease or illness. All products are strictly for research purposes only. Please refer to the TERMS OF USE for more information.
