MGF (PEG-MGF) is a splice variant of the IGF produced by a frame shift if the IGF gene and PEGylated to improve stability. MGF (PEG-MGF), or PEGylated Mechano Growth Factor, is a new and innovative form of the IGF produced by a frame shift if the IGF gene, namely Mechano Growth Factor (MGF), which is PEGylated to improve stability that outperforms natural MGF many times over. MGF is a splice variant of the IGF gene which increases stem cell count in the muscle and allows for muscle fibers to fuse and mature. This is a process required for growth of adult muscle. Natural MGF is made locally and does not travel into the bloodstream. Synthetic MGF is water based and when administered intramuscularly, travels into the bloodstream. MGF is only stable in the blood stream for only a few minutes. Research has shown that MGF (PEG-MGF) helps increase the muscle stem cell count, so that more may fuse and become part of adult muscle cells.

MGF (PEG-MGF) exhibits local effects in skeletal muscle and without cannot travel through the body without modification. The problem with synthetic Mechano Growth Factor (MGF) is that it is introduced intramuscularly and is water based so it goes into the blood stream. When used this way, Mechano Growth Factor (MGF) only remains stable in the blood stream for a few minutes. Biologically produced MGF is made locally and does not enter the bloodstream. It is also short acting so stability is not an issue. By PEGylating the Mechano Growth Factor (MGF) it is almost as efficient as local produced Mechano Growth Factor (MGF) when used intramuscularly.

Dosage

Since MGF (PEG-MGF) is considered to be more bioavailable, you will only need to inject it to your body 2 to 3 times a week. MGF (PEG-MGF) remains to be effective few days after self-administration. The average recommended dosage for this peptide is 1000 mcg every 24 hours. You may inject it subcutaneously an hour or 2 before training to mimic the physiologic secretion of IGF 1. Recommended cycle duration is between 5 to 6 weeks.

Ingredients

MGF (PEG-MGF): 5mg PEG-Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-Arg-Lys-NH2

Stoarge

Below -20 degrees or the freezer. Once reconstituted -8 degrees or the fridge is acceptable.

Medical References

1. Kandalla, PK, Goldspink, G, Butler-Browne, G & Mouly, V 2011, ‘Mechano Growth Factor E peptide (MGF-E), derived from an isoform of IGF-1, activates human muscle progenitor cells and induces an increase in their fusion potential at different ages’, Mechanisms of Ageing & Development, vol. 132, no. 4, pp. 154–162
2. Sha, Y( 1,2 ), Yang, L( 1,2 ) & Lv, Y( 1,2 ) n.d., ‘MGF E peptide improves anterior cruciate ligament repair by inhibiting hypoxia-induced cell apoptosis and accelerating angiogenesis’, Journal of Cellular Physiology, vol. 234, no. 6, pp. 8846–8861
   

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