PUMP (S-23) is an orally active non-steroidal SARM with a very high binding affinity to androgen receptors. This makes it stronger than other popular SARMS like MAINTAIN (MK-2866) or MASS (S-4). Therefore, the main effects of PUMP (S-23) are increased muscle mass, decreased fat mass, and a decrease in the size of the prostate.

Additionally, in a study done on rats a dose equivalent to 15 milligrams (mg) for a 180lb male was shown to also increase bone mineral density, as well as promote muscle mass growth and fat loss. Hence, PUMP (S-23) is versatile in that it can be used for bulking and for cutting.

A 2009 study performed on rats showed potential for S-23 to be used as a male contraceptive. In this study, six rats were given a dose of 0.1 mg per day for 10 weeks. As a result, both LH (Luteinizing Hormone) and FSH (Follicle-Stimulating Hormone) levels decreased. These effects were statistically significant, since four of the six rats had no sperm in the testis. What’s more, none of the rats was able to impregnate a female rat during mating trials. However, this contraceptive effect was temporary – after just 100 days from last dose the infertility was reversed, and there was a 100% pregnancy rate.

Dosage

Concentration: 20mg/mL

Volume: 30mL

A typical dosage of is 20mg (1ml). Each bottle is 30ml dosed at 20mg/ml and will last for 30 days at suggested dosage.

Ingredients/ HPLC Purity Report

PUMP (S-23): (2S)-N-(4-cyano-3-trifluoromethylphenyl)-3-(3-fluoro-4-chlorophenoxy)-2-hydroxy-2-methyl-propanamide, Food-grade USP glycol, food-grade ethyl alcohol and essential oils.

Please email [email protected] for the latest HPLC purity report.

Medical References

1. Thevis, M, Gerace, E, Thomas, A, Beuck, S, Geyer, H, Schlörer, N, Kearbey, JD, Dalton, JT & Schänzer, W 2010, ‘Characterization of in vitro generated metabolites of the selective androgen receptor modulators S-22 and S-23 and in vivo comparison to post-administration canine urine specimens’, Drug testing and analysis, vol. 2, no. 11–12, pp. 589–598
2. Marhefka CA, Gao W, Chung K, Kim J, He Y, Yin D, Bohl C, Dalton JT, Miller DD. Design, synthesis, and biological characterization of metabolically stable selective androgen receptor modulators. Journal of Medicinal Chemistry. 2004 Feb 12;47(4):993-8.
3. Jones A, Chen J, Hwang DJ, Miller DD, Dalton JT. Preclinical characterization of a (S)-N-(4-cyano-3-trifluoromethyl-phenyl)-3-(3-fluoro, 4-chlorophenoxy)-2-hydroxy-2-methyl-propanamide: a selective androgen receptor modulator for hormonal male contraception. Endocrinology. 2009 Jan;150(1):385-95

Storage

Cool and dark space like a cupboard or pantry.

No statements made on this page have been evaluated by the Bundesministerium für Gesundheit (BMG) or the Therapeutic Goods Administration (TGA). These products are not intended to treat, cure or prevent any disease or illness. All products are strictly for research purposes only. Please refer to the TERMS OF USE for more information.